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However, there are considerable risks, demonstrated by clinical reports, of unappreciated high volumes of gastric contents even when fasting guidelines are followed

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This decrease in muscle mass can lead to: A reduction in physical strength and muscle function. An acceleration in the ageing process. An exacerbation of sarcopenic obesity, a condition characterised by high fat mass and low muscle mass, linked to poor cardiovascular performance and increased mortality

Cambridge: Cambridge University Press (2007)